If your knees ache, they have lots of company. Over 46 million Americans suffer from arthritis. Osteoarthritis (OA) of the knee is the most common type, and the way it affects the knee is painfully simple.

Three bones meet up at the knee joint: the end of the thigh bone (femur), the top of the shin bone (tibia), and the knee cap (patella). Those bones are cushioned by synovial fluid and cartilage.

Osteoarthritis causes the lubricating properties of the synovial fluid in the knee joint to diminish, resulting in less protection and cushioning. In addition, osteoarthritis wears down the cartilage, resulting in your bones grinding against each other. That grinding hurts. You can feel it climbing stairs, working in the garden, walking or just bending your knees to sit. It may even keep you up at night.


Arthritis is a disease that typically worsens over time, so it is common for treatment to involve more than one approach and to change over time. Together, you and your doctor can determine the best treatment options for you. The good news is knee arthritis pain can be treated.

Viscosupplementation Treatment

Synovial fluid, containing hyaluronan, is a naturally occurring lubricant or cushion present in your knee joint that helps your knee joints work efficiently and without friction.

Synovial fluid properties degenerate in the early stages of osteoarthritis. As it breaks down, joints can become painful. Fortunately, there is a natural treatment available that injects supplemental hyaluronate into the knee that cushions, lubricates and improves knee function.

Gel-One Hyaluronate

Hyaluronate injections have been available in the US for a number of years, but only Gel-One Hyaluronate delivers a complete treatment using a highly purified, 3 mL, single injection. Gel-One Hyaluronate offers the following important benefits.

  • Convenience of a single injection with less office visits
  • Safe, effective, and complete treatment volume of 3 mL
  • Supplements the natural lubrication and cushioning in the knee joint